What is Desloratadine?

Desloratadine belongs to the group of the most effective antiallergic drugs and is a blocker of H1 histamine receptors. The drug has a long-lasting effect and is the primary active metabolite of the substance loratadine. Desloratadine inhibits the release of histamine and C4 leukotriene from basophils, which prevents the development of allergic reactions in the body manifested by rash, itching, sneezing, runny nose or lacrimation.

In addition, this drug is effective not only against itching and the development of allergies, but also has an antiedematous effect. It prevents the release of body fluid and reduces the permeability of the vascular capillary wall, thereby preventing the development of edema. This drug does not cause drowsiness and does not affect the speed of psychomotor reactions if the dose does not exceed 7.5 milligrams.

Desloratadine belongs to the 3rd generation drugs, so it is safe and effective in treating chronic allergic reactions as well as urticaria. The drug is prescribed only by a doctor, self-treatment is inadmissible.

Side effects

Unwanted effects of Desloratadine

These include: 

• fatigue, drowsiness;
• vertigo;
• dry mouth mucous membranes;
• migraines;
• increased anxiety;
• atony;
• abdominal pain;
• nausea;
• unpleasant aftertaste in the mouth.

The above undesirable effects are, for the most part, insignificant and can compensate on their own after a period of time. If the side effects worsen, such as shortness of breath, seek medical advice immediately.

Contraindications for use

Desloratadine tablets should not be taken by persons: 

1. Having hypersensitivity to the active substance of the drug or any of its components.

2. Women during pregnancy and lactation period, because the reception of this drug can adversely affect the health of the fetus.

3. People suffering from phenylketonuria, i.e. impaired amino acid metabolism, which is accompanied by mental retardation with cognitive and behavioral disorders.

4. People using concomitantly with desloratadine such drugs as Ketoconazole/erythromycin. This drug combination increases the amount of Desloratadine in the bloodstream, which may cause multiple adverse reactions. 

Desloratadine is synthesized in the liver and is eliminated by the kidneys. It is recommended to avoid taking Desloratadine in people with a history of liver or kidney disease.

Dosage

The dosage of the drug Desloratadine depends on certain aspects, namely the age, body weight, well-being of the patient, as well as the reaction of his body to the ongoing treatment.

It is necessary to observe the doctor's orders, as well as to study the instructions for use of the drug in advance.

Adults and children over 12 years of age should use Desloratadine 5 mg once a day.

For children aged:

• 2-5 years of age Desloratadine drug in syrup 2.5 milliliters, which corresponds to 1.25 milligrams of Desloratadine - once a day;
• 6-11 years old the drug desloratadine in syrup 5 ml, which corresponds to 2.5 milligrams of Desloratadine - once a day.

Please note, when taking the drug, you should follow the recommendations of the treating doctor. It is contraindicated to adjust the dosage of the drug or the frequency of its administration on your own.

What if I miss taking the medicine?

If you miss taking the medicine, you should take it at the scheduled time the next day. It is categorically not recommended to additionally replenish the missed dose of the drug or take a double dose at one time.

What is the difference between Desloratadine and Loratadine?

Desloratadine is the active metabolite of loratadine, what does this mean? The fact is that desloratadine is internally formed from loratadine. Desloratadine 5 mg tablet, have a more potent and prolonged effect, unlike loratadine. 

Both medications are effective against allergies. Therefore, it is up to the attending physician to decide which drug is best for a particular situation, based on the patient's medical history and the individual characteristics of the patient's body.

Desloratadine otc

Buy Desloratadine is available at our online pharmacy. You can read the price, availability, and instructions for use before you purchase the drug. Do not self-medicate. Before you start taking it, you should consult your doctor and get a prescription. If you do not have the opportunity to see a doctor, but you need Desloratadine, you can get it from a pharmacy doctor.