rn Please consult your physician before taking any medication. Diflucan 100mg 10 Caps Generic Name: fluconazole (floo KOE na zole) Brand Names: Diflucan (Pfizer) What is fluconazole? Fluconazole is an antifungal antibiotic. Fluconazole is used to treat infections caused by fungus, which can invade any part of the body including the mouth, throat, esophagus, lungs, bladder, genital area, and the blood. Fluconazole is also used to prevent fungal infection in people with weak immune systems caused by cancer treatment, bone marrow transplant, or diseases such as AIDS. Fluconazole may also be used for purposes other than those listed in this medication guide.