Levoxyl is a thyroid medication that replaces a hormone that regulates metabolism and energy levels in the body. It is prescribed for insufficient production of the hormone. Effective with hyperthyroidism, enlarged thyroid gland.
Euthyrox is a thyroid medication, which has an anabolic effect if taken in a minimum dose. When taken in medium doses, there is stimulation, increased tissue oxygen requirements, improved metabolism, heart, CNS, and pituitary function.
After ingestion, adsorption from the gastrointestinal tract is 48-79%. If the drug is taken on an empty stomach, its absorption is improved. The maximum amount in the blood is reached after 6 hours. Distribution occurs in the liver as well as in the brain and muscles. The period of excretion is 6-7 days, 15% is excreted unchanged.
- Reduced hormone levels.
- Prophylactic measures and therapy after thyroid goiter resection.
- Treatment of cancer after surgery.
- Diffuse toxic goiter.
- Before thyroid suppression test.
Levoxyl generic is prescribed only by a doctor after the examination. Taking into account the patient's condition and the course of the disease, the dose of the drug may be 12.5-200 mcg once a day. It should be taken 20-30 minutes before meals. For the differential diagnostic test of thyroid suppression - 3 mg or 200 mcg 1 time/day for 2 weeks is prescribed. If the patient has missed the scheduled dose, they should take it as soon as possible. If the next dose is scheduled, it is not necessary to take the previous dose to avoid an overdose.
In the case of insufficient hormones, treatment begins with a dose of 25-100 mcg/day. For maintenance, you should take 125-250 mcg/day. For children, the drug should be started with 12.5-50 mcg/day and increased to - 100-150 mcg per square meter of body. If the child has a congenital lack of hormone production at the age of up to 6 months, 8-10 mcg/kg per day is prescribed. At 6-12 months of age, treatment is given at a rate of 6-8 mcg/kg/day. At 1-5 years of age the dose is increased to - 5-6 mkg/kg/day, and at 6-12 years of age, it is 4-5 mkg/kg/day.
Endemic goiter therapy begins with 50 mcg/kg/day. Gradually, the dose reaches the optimal value of 100-200 mcg/day. Euthyroid goiter and prophylactic measures to prevent recurrence after resection require 75-200 mcg/day for adult therapy and 12.5-150 mcg/day for pediatric treatment. A dose of 150-300 mcg/d is prescribed if the patient has a history of thyroid cancer after surgical treatment.
Levoxyl generic can cause hyperthyroidism when taking too large doses of the drug. As a result, there is a disruption of the cardiovascular system. Headache, tremor, sleep disturbance, restlessness, muscle weakness, cramps, menstrual disorders appear.
The drug has the following contraindications:
- Individual intolerance of individual components;
- Acute myocardial infarction and myocarditis;
- Problems with adrenal function.
Caution should be exercised when prescribing in disorders of the heart and vascular function, high blood pressure, diabetes mellitus, long-term hormone deficiency - hypothyroidism. In such pathologies, treatment with the drug begins with minimal doses, which increase gradually with long intervals.
If a patient is diagnosed with hypothyroidism, first the state of the adrenal glands is checked to exclude their insufficiency. If pathology is detected, therapy with glucocorticosteroids is carried out, only after that are thyroid hormones prescribed.
When treating elderly patients, therapy should be started with the minimum amount. For the thyroid suppression test in patients with diabetes mellitus, more antidiabetic agents are needed.
Levoxyl 137 mcg is prescribed in pregnancy only in a strictly prescribed dose. It should not be taken during pregnancy together with thyrostatic agents due to the increased risk of fetal hormone reduction. Children are allowed to take the drug in doses and dosage forms that are appropriate for their age.
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